Glycine
An amino acid involved in protein synthesis and inhibitory signaling pathways.
$139.90
In stock
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Clean formulas for clean living.
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Comfort was designed around the difficult overlap between physical discomfort, muscle tension, nervous-system settling and restorative sleep that many people with complex chronic illness navigate at night.
Instead of treating every wellness priority as a separate bottle, Comfort brings eight complementary components into one coordinated routine.

Complex chronic illness rarely stays in one lane. Comfort is organized around overlapping nutritional and physiological support needs rather than a single symptom in isolation.
Every component has a distinct job. Together, they create a simpler daily foundation built around the priorities of this Program.
An amino acid involved in protein synthesis and inhibitory signaling pathways.
Supports normal cellular balance and nervous-system function.
An amino acid from tea commonly used to support relaxation without daytime sedation.
A coordinated botanical component intended to complement a consistent nighttime routine.
Sustained-release melatonin supports normal sleep-wake signaling over the night.
Supports normal muscle relaxation, nerve signaling and energy metabolism.
Supports normal joint lubrication and connective-tissue hydration.
Supports healthy inflammatory and antioxidant pathways relevant to physical comfort.

The Program format is designed to make a complicated wellness routine easier to understand, organize and follow consistently.
The point is not to make eight ingredients do the same thing. It is to cover complementary nutritional roles—foundational nutrients, cellular processes, antioxidant defenses and the Program’s more targeted support priorities—without asking you to build and manage a shelf full of separate bottles.
One coordinated daily Program. Eight deliberately selected components. A formulation built around the realities of navigating a complicated body.
Complexa Programs support normal body structure and function; they are not treatments for hEDS, POTS, MCAS or any other disease.
There is no universal timeline. What you notice depends on baseline nutrient status, diet, absorption, medications, consistency and your individual physiology.
Focus first on tolerance and consistency. Some people may notice changes in areas influenced by nutritional sufficiency, muscle function or daily routine sooner than others.
Look for patterns rather than a single dramatic moment: steadier support, easier routine adherence, recovery or other changes relevant to the Program’s nutritional targets.
Slower processes—including nutritional repletion and structural or metabolic support—may require longer-term consistency before they can be meaningfully evaluated.
These timeframes are educational, not a promise of results. Supplements affect people differently. Discuss new supplements with a qualified healthcare professional when you take medications, are pregnant or nursing, or manage a medical condition.
Comfort was designed around the difficult overlap between physical discomfort, muscle tension, nervous-system settling and restorative sleep that many people with complex chronic illness navigate at night. If another area is more central to your daily experience, explore the other Complexa Programs to find the closest fit for your priorities.
Every Complexa Program is built around a different set of systems, symptoms, and everyday priorities. Explore the options below to find the Program that best matches what you are navigating.

Coordinated support for overlapping connective-tissue, autonomic, mast-cell, and cellular-energy demands.
Explore Trifecta →
Foundational micronutrient, cellular-energy, mitochondrial, antioxidant, and metabolic support for complex chronic illness.
Explore Core →
Focused support for hypermobility, connective tissue, joint comfort, collagen formation, and musculoskeletal recovery.
Explore Connect →
Antioxidant, immune, and healthy inflammatory-balance support for people navigating complex chronic illness.
Explore Composure →
Targeted nutritional support for brain fog, cognitive fatigue, mental energy, and neurological function.
Explore Coherence →
Digestive, intestinal-barrier, antioxidant, and inflammatory-balance support for complex chronic illness.
Explore Converge →